Guitar player Pauline France lists Things Women Who Play Guitar Are Tired of Hearing — and What You Should Say Instead in Guitar World. It's not about looks, it's about skill. Here's one:
I never figured you’re the type to play guitar. Oh shucks, I didn’t know there was a type. Please, enlighten me. Last time I checked all you needed were two hands, 10 fingers (…and a brain). Wink.